2011 Fiscal Year Final Research Report
Quantitative Analysis of Morphogenesis by Whole-animal 4D-imaging
| Project/Area Number |
21770241
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Developmental biology
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| Research Institution | Keio University |
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Principal Investigator |
HOTTA Kohji 慶應義塾大学, 理工学部, 講師 (80407147)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 末梢神経 / 3Dライブイメージング / 進化 / 3D / ホヤ / 神経管閉鎖 |
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| Research Abstract |
To understand morphogenesis at single-cell-level in chordate organogenesis period, ascidian embryo was used in this study. By 3D imaging of ascidian larva, a novel peripheral neuron network structure was found at larval outer tunic. Computer model of the tailbud embryo were made. By 3D-live(4D) imaging of neural tube closure, it was suggested that two independent cell movements accomplish the closure. Thus high-resolution imaging of ascidian embryogenesis enables us to understand how each cell cause morphogenesis of tissue, organ and whole-animal level.
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Research Products
(16 results)
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[Presentation] ASNET : Actin-based network structure in the tunic of ascidian larva2010
Author(s)
Kohji HOTTA, Hiroshi Q TERAKUBO, Mitsuru Nakamura, Yoko NAKAJIMA, Yasunori SASAKURA, Takeo HORIE, Alu KONNO, Hiroki TAKAHASHI, Kazuo INABA, Kotaro OKA
Organizer
Society for Developmental Biology 69th Annual Meeting-Jointly with Japanese Society of Developmental Biologists
Place of Presentation
New Mexico, USA
Year and Date
2010-08-08
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[Presentation] Ascidian dendritic network in tunic2010
Author(s)
Kohji HOTTA, Hiroshi Q TERAKUBO, Yoko NAKAJIMA, Alu KONNO, Takeo HORIE, Hiroki TAKAHASHI, Yasunori SASAKURA, Kazuo INABA, Kotaro OKA
Organizer
2ND JOINT MEETING OF THE SFBD AND JSDB 2010-From Cells to Organs
Place of Presentation
Institut Pasteur, Paris, France
Year and Date
2010-05-27
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