Relationship of plasma asymmetrical dimethylarginine to 7-year incidence of coronary artery calcification in Japanese

2010 Fiscal Year Final Research Report

• Project/Area Number: 21790578
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Public health/Health science
• Research Institution: Shiga University of Medical Science
• Principal Investigator: NAGASAWA Shin-ya Shiga University of Medical Science, 生活習慣病予防センター, 特任助教 (30510341)
• Project Period (FY): 2009 – 2010
• Keywords: 成人保健 / 心腎連関

Research Abstract

Findings on the relationship of plasma asymmetrical dimethylarginine (ADMA) to atherosclerosis have been scarce. And the finding about relationship to the future incidence of coronary artery calcification (CAC) has been lack.
We attempted to evaluate the association in a 7-year follow-up of population-based samples in Japan.
Higher level of ADMA was independently associated with the future incidence of CAC in Japanese men. ADMA may be a new important predictor for progression of atherosclerosis.

Research Products

• [Presentation] Relationship of plasma asymmetrical dimethylarginine to 7-year incidence of coronary artery calcification in Japanese : the ERA-JUMP Study. (2011)
  • Author(s): Shin-ya Nagasawa.
  • Organizer: Nutrition, Physical Activity and Metabolism/Cardiovascular Disease Epidemiology and Prevention 2011 Scientific Sessions (American Heart Association)
  • Place of Presentation: Atlanta(USA)
  • Year and Date: 2011-03-25
• [Presentation] Relationship of plasma asymmetrical dimethylarginine to 7-year incidence of coronary artery calcification in Japanese : the ERA-JUMP Study (2011)
  • Author(s): 長澤晋哉
  • Organizer: 日本循環器学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2011-03-19