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2011 Fiscal Year Final Research Report

oriental medicine has an effect on cancer : Molecular Pathological investigation about antitumor effect of Juzen-taiho-to

Research Project

  • PDF
Project/Area Number 21790624
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field General internal medicine (including Psychosomatic medicine)
Research InstitutionKitasato University (2010-2011)
University of Toyama (2009)

Principal Investigator

TAKAHASHI Hiroyuki  北里大学, 医学部, 講師 (60377330)

Co-Investigator(Renkei-kenkyūsha) TAKANO Yasuo  地方独立行政法人神奈川県立病院機構神奈川県立がんセンター, 臨床研究所, 所長 (60142022)
Project Period (FY) 2009 – 2011
Keywords十全大補湯 / 抗腫瘍効果 / 抗癌剤 / SV40トランスジェニックマウス
Research Abstract

It was elucidated that Juzen-taiho-to had no influence on gene expression of tumor itself and no direct antitumor effect. But it was clarified that Juzen-taiho-to induced the production of proteins for phylaxis and enzymes for drug metabolism without hepatotoxicity.

  • Research Products

    (5 results)

All 2011 2010 2009

All Journal Article (3 results) Presentation (2 results)

  • [Journal Article] Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis2011

    • Author(s)
      Takahashi H, Wang JP, Zheng HC, Masuda S, Takano Y.
    • Journal Title

      Histol Histopathol

      Volume: 26 Pages: 663-71

  • [Journal Article] Parafibromin expression is an independent prognostic factor for colorectal carcinomas2011

    • Author(s)
      Zheng HC, Wei ZL, Xu XY, Nie XC, Yang X, Takahashi H, Takano Y.
    • Journal Title

      Hum Pathol

      Volume: 42 Pages: 1089-102

  • [Journal Article] The nuclear to cytoplasmic shift of ING5 protein during colorectal carcinogenesis with their distinct links to pathologic behaviors of carcinomas2011

    • Author(s)
      Zheng HC, Xia P, Xu XY, Takahashi H, Takano Y.
    • Journal Title

      Hum Pathol

      Volume: 42 Pages: 424-33

  • [Presentation] 難治性黄疸の原因と考えられた総胆管peribiliary cystの一剖検例2010

    • Author(s)
      高橋博之, 三輪重治, 野本一博, 林伸一, 常山幸一, 高野康雄
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京
    • Year and Date
      20100427-29
  • [Presentation] 鋸歯状ポリープ-腺癌経路を示唆する癌と臨床病理学的事項の関係の検討2009

    • Author(s)
      高橋博之, 中嶋隆彦, 藤本誠, 三輪重治, 野本一博, 林伸一, 常山幸一, 高野康雄
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都
    • Year and Date
      20090501-03

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Published: 2013-07-31  

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