2010 Fiscal Year Final Research Report
Isolation of human renal stem cells from urine of pediatric patients with nephropathy
| Project/Area Number |
21790966
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
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| Research Institution | Tohoku University |
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Principal Investigator |
KUMAGAI Naonori Tohoku University, 病院, 助教 (40400329)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 尿中落下細胞 / 腎臓組織幹細胞 / 腎臓間葉系幹細胞 / 再生医療 / side population cell / 小児 / 腎疾患 / フローサイトメーター |
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| Research Abstract |
Renal stem cells such as CD24+CD133+podocalyxin+ cells, CD133-CD146+ cells, and side population cells were cultured from the urine of pediatric patients with nephropathy. These cells showed the ability to differentiate into various types of renal cells. Urine may be a useful tool for regenerative medicine for kidney disease.
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