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2010 Fiscal Year Final Research Report

Basic research of incretins for pancreas development and pancreas cancer progression

Research Project

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Project/Area Number 21791283
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Digestive surgery
Research InstitutionKyoto University

Principal Investigator

KOIZUMI Masayuki  Kyoto University -> 京都大学, 医学研究科, 助教 (90512351)

Project Period (FY) 2009 – 2010
Keywords膵発生 / 膵癌 / インクレチン / GIP / GLP-1
Research Abstract

Incretins are synthesized and released at enteroendocrine cells, and stimulate beta cells in pancreas to maintain blood glucose. Their distributions and functions were investigated by using three dimensional exvivo culturing systems of mouse pancreas. The role of incretins in pancreatic cancer development are remains to be elucidated.

Research Products

(2 results)

All 2011 Other

All Journal Article Presentation

  • [Journal Article] Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine.2011

    • Author(s)
      Furuyama K, Kawaguchi Y, Akiyama H, Horiguchi M, Kodama S, Kuhara T, Hosokawa S, Elbahrawy A, Soeda T, Koizumi M, Masui T, Kawaguchi M, Takaori K, Doi R, Nishi E, Kakinoki R, Deng JM, Behringer RR, Nakamura T, Uemoto S.
    • Journal Title

      Nat Genet. 43(1)

      Pages: 34-41

  • [Presentation] 膵発生におけるGIP(Glucosedependent insulinotropic peptide)の発現とその機能

    • Organizer
      膵(基礎研究),ハイブリッドポスター,第109回日本外科学会定期学術集会HP-148-6

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Published: 2012-02-12   Modified: 2016-04-21  

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