2011 Fiscal Year Final Research Report

Study for effects of combination of Intracytoplasmic sperm injection and artificial oocyte activation

Research Project

Project/Area Number	21791568
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Obstetrics and gynecology
Research Institution	Fukushima Medical University
Principal Investigator	SUGANUMA Ryota 福島県立医科大学, 医学部, 講師 (30528211)
Project Period (FY)	2009 – 2011
Keywords	生殖医学 / 卵細胞質内精子注入法
Research Abstract	Combination of ICSI and artificial oocytes activation immediately after ICSI was useful for infertility animals which spermatozoa were depress the sperm oocytes activation factors. Taking long time after ICSI in unactivated status(oocytes remains at MII) is caused to damage on sperm chromosomes and that is caused to worth embryos development. We suggest that activating oocytes at checking the presence of 2nd polar body might be useful for reduce damages, and that might be useful for"rescue"ICSI oocytes going to"unfertilized".