2010 Fiscal Year Final Research Report
Placenta as a target of influenza virus infection
| Project/Area Number |
21791574
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Nihon University |
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Principal Investigator |
AIZAWA Shihoko Nihon University, 医学部, 助手 (30513858)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 微生物 / 胎盤 / インフルエンザウイルス |
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| Research Abstract |
We report here placenta as a target organ of influenza A virus. A choriocarcinoma cell line and immortalized human invasive trophoblasts were challenged with an influenza virus strain A/Udorn/72 and /or clinical isolate of H1N1/09 influenza virus. We observed viral replication in both viruses, while cytotoxicity was less prominent in H1N1/09.
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