2010 Fiscal Year Final Research Report
Role of endolymphatic Ca2+ in reperfusion after acute ischemia
Project/Area Number |
21791653
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Otorhinolaryngology
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Research Institution | Osaka Medical College |
Principal Investigator |
MORI Atsuko (高巻 京子) Osaka Medical College, 医学部, 助教 (40368105)
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Project Period (FY) |
2009 – 2010
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Keywords | 内耳電気生理 / 蝸牛内直流電位 / 蝸牛管抵抗 / 細胞内カルシウム / 低酸素負荷 |
Research Abstract |
We measured the changes in EP and cochlear partition resistance (CoPR) induced by asphyxia. The CoPR was decreased after the perfusion with control artificial endolymph, and was increased after the asphyxia. The perfusion with artificial endolymph containing BAY K8644 decreased both the CoPR and the EP, and the CoPR was increased by the asphyxia. These results suggest that increase in the CoPR induced by the asphyxia might not be mediated by the elevation of cytosolic Ca^<2+> in the cochlear cells.
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[Journal Article] Planned fractionated boron neutron capture therapy using epithermal neutrons for a patient with recurrent squamous cell carcinoma in the temporal bone : a case report.2009
Author(s)
Haginomori S, Miyatake S, Inui T, Araki M, Kawabata S, Takamaki A, Lee K, Takenaka H, Kuroiwa T, Uesugi Y, Kumada H, Ono K
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Journal Title
Head Neck 31
Pages: 412-418
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[Presentation]2009
Author(s)
Yoshiaki Mori, Masahito Watanabe, Takaki Inui, Atsuko Mori, Yoshitugu Nimura, Akihito Mineharu, Michitoshi Araki, Hiroshi Takenaka, Takahiro Kubotam
Organizer
XXXVI International Congress of Physiological Sciences
Place of Presentation
京都市・京都国際会館
Year and Date
20090700
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