2010 Fiscal Year Final Research Report
Development of a novel disinfection technique based on photodynamic therapy
| Project/Area Number |
21791932
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
NAKAMURA Keisuke 東北大学, 未来科学技術共同研究センター, 助教 (30431589)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 光線力学療法 / 一重項酸素 / 活性酸素 / 殺菌 |
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| Research Abstract |
In the present study, it was demonstrated that singlet oxygen generated in photodynamic therapy could effectively kill Streptococcus aureus. In addition, a quantitative analytical method for singlet oxygen generated in photodynamic therapy has been established. It was demonstrated that electron spin resonance technique using sterically hindered amine was suitable for the measurement. The analysis showed that the yield of singlet oxygen increased with the irradiation time and the concentration of photosensitizer.
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