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2010 Fiscal Year Final Research Report

A development of new treatment for oral cancer with beta4 integrin and associated proteins.

Research Project

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Project/Area Number 21792011
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionEhime University

Principal Investigator

ARAMOTO Takayoshi  Ehime University, 医学部附属病院, 助教 (00380220)

Project Period (FY) 2009 – 2010
Keywordsbeta4 integrin / ヘミデスモゾーム / siRNA
Research Abstract

We concluded that the inhibition of beta4 integrin which is the member of integrin family, can interaction with ECM, changed cell morphology, cell motility, and decreased cell invation in oral squamous cell lines. Our data suggested that beta4 integrin is greatly taken part in cancer cell invation.

  • Research Products

    (1 results)

All 2009

All Journal Article (1 results) (of which Peer Reviewed: 1 results)

  • [Journal Article] β4インテグリンによる口腔扁平上皮癌細胞の運動制御機構(総説)2009

    • Author(s)
      荒本孝良, Randall H Kramer, 浜川裕之
    • Journal Title

      口腔組織培養学会誌 18(2)

      Pages: 15-20

    • Peer Reviewed

URL: 

Published: 2012-02-13   Modified: 2016-04-21  

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