Establishment of jaw bone regeneration technique using mesenchymal stem cells.

2010 Fiscal Year Final Research Report

• Project/Area Number: 21792038
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Surgical dentistry
• Research Institution: Matsumoto Dental University
• Principal Investigator: NIWA Takashi Matsumoto Dental University, 歯学部, 助手 (60507680)
• Project Period (FY): 2010 – 2011
• Keywords: 口腔外科学一般

Research Abstract

Establishment of jaw bone regeneration technique using mesenchymal stem cells in accordance with the culture of the good manufacturing practices(GMP). Bone marrow samples were aspirated from the posterior iliac crest and Human MSC grew to approximately 1×10^7 cells within 3 weeks. Mycoplasmal and bacterial infection was not observed during overall autologous MSC cultivation or transportation between facilities.This system is safe and could be applied to regeneration medicine for the head and neck region.

Research Products

• [Presentation] 培養骨髄間葉系細胞移植による骨再生療法の確立 (2011)
  • Author(s): 丹羽崇, 中澤高志, 寺本祐二, 高橋美穂, 上松隆司
  • Organizer: 日本口腔インプラント学会関東・甲信越地方会
  • Place of Presentation: 神奈川
  • Year and Date: 2011-02-13
• [Presentation] 多血小板血漿を併用した培養骨髄間葉系細胞移植による骨再生療法の確立 (2010)
  • Author(s): 丹羽崇, 中澤高志, 寺本祐二, 高橋美穂, 上松隆司
  • Organizer: 日本口腔インプラント学会中部地方会
  • Place of Presentation: 岐阜
  • Year and Date: 2010-11-13
• [Presentation] Cell processing system for bone regeneration (2010)
  • Author(s): Y.Teramoto, T.Uematsu, T.Niwa, M.Takahashi, R.Doto, S.Shimodaira, T.Uemura, M.sato, H.Tahara, S.Wakitani, N.Udagawa, K.Furusawa
  • Organizer: The IADR 84^<th> General Session & Exhibition
  • Place of Presentation: Barcelona
  • Year and Date: 2010-07-15
• [Presentation] Cell Processing Centerを利用した骨再生療法の確立 (2010)
  • Author(s): 寺本祐二, 上松隆司, 堂東亮輔, 高橋美穂, 丹羽崇, 高田匡基, 丸川和也, 下平滋隆, 脇谷滋之, 中村美どり, 八上公利, 宇田川信之, 古澤清文
  • Organizer: 第9回日本再生医療学会総会
  • Place of Presentation: 広島
  • Year and Date: 2010-03-19
• [Presentation] 培養骨髄間葉系細胞を骨再生療法に適用するための基礎的研究 (2009)
  • Author(s): 寺本祐二, 上松隆司, 堂東亮輔, 高橋美穂, 高田匡基, 丹羽崇, 丸川和也, 古澤清文
  • Organizer: 第13回日本顎顔面インプラント学会
  • Place of Presentation: 佐賀
  • Year and Date: 2009-12-12
• [Presentation] 培養自己骨髄間葉系細胞を用いた骨再生療法の基礎的研究 (2009)
  • Author(s): 寺本祐二, 上松隆司, 堂東亮輔, 高橋美穂, 高田匡基, 丹羽崇, 丸川和也, 古澤清文
  • Organizer: 第46回日本口腔組織培養学会学術大会
  • Place of Presentation: 東京
  • Year and Date: 2009-12-05