2010 Fiscal Year Final Research Report
Association between periodontal disease and polymorphism related type 2 diabetes mellitus
| Project/Area Number |
21792147
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Social dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
MATSUMOTO Sayaka Niigata University, 医歯学総合病院, 医員 (50515749)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 予防歯科 / 臨床疫学 |
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| Research Abstract |
The aim of this study was to investigate association between genetic factor (adiponectin gene at SNP276 and94) and periodontal disease in type 2 diabetes mellitus patients. Serum adiponectin concentration in subjects with GG type at SNP276 or TT type at SNP94 had lower than those without these SNPs (p=0.034). The subjects with these SNPs were also higher levels in periodontal status parameters, however there were not significant differences. Our results suggested that adiponectin gene at SNP94 and 276 might be associated with periodontal status.
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