2010 Fiscal Year Final Research Report
Development of Functional Polysaccharide-Biomaterials Inducing Organic-Inorganic Hybrid Nano-structure
| Project/Area Number |
21800086
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Numazu College of Technology |
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Principal Investigator |
YAMANE Setsuko Numazu College of Technology, 物質工学科, 助教 (00550477)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 有機-無機ハイブリッド / 糖 / リン酸カルシウム / DDS |
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| Research Abstract |
Organic-inorgenic hybrid hydrogels were synthesized as a functional scaffold for regeneration of the defective parts of bone and teeth. Hydrophobized polysaccharides nanogels were used as nucleus for calcium phosphate mineralization. These hybrid nanoparticles were then cross-linked to prepare hybrid hydrogel. The hybrid hydrogels inducted nano-sized helical ribbon of intermediate structure of formation of hydroxyapatite.
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