2010 Fiscal Year Final Research Report
Genetic analyses of the function of REM sleep
| Project/Area Number |
21800090
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Neuroscience in general
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
HAYASHI Yu The Institute of Physical and Chemical Research, 行動遺伝学技術開発チーム, 基礎科学特別研究員 (40525812)
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| Project Period (FY) |
2009 – 2010
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| Keywords | REM睡眠 / マウス / 遺伝学 |
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| Research Abstract |
REM sleep, a physiologic state responsible for dreaming, is unique to certain vertebrate species and thus might be involved in higher-order brain functions. Yet the roles of REM sleep remain elusive. Here, to overcome the problems of conventional methods to inhibit REM sleep (side-effects such as stress and rebound), I adopted a genetic approach. I established transgenic mice in which a neural-activity inhibiting gene can be induced specifically in the REM sleep center.
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