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2010 Fiscal Year Final Research Report

Mechanisms in the teleost brain for generating sex differences

Research Project

  • PDF
Project/Area Number 21880017
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field General fisheries
Research InstitutionThe University of Tokyo

Principal Investigator

OKUBO Kataaki  The University of Tokyo, 大学院・農学生命科学研究科, 准教授 (10370131)

Project Period (FY) 2009 – 2010
Keywords性差 / メダカ / 脳 / 魚類 / 遺伝子発現
Research Abstract

We examined the function of several genes that show sexually dimorphic expression patterns in the medaka brain in order to understand the mechanisms in the teleost brain for generating sex differences. Medaka were treated with the antagonists and specific antibodies for the sexually dimorphic genes, as well as their translational products, and subjected to behavioral analyses. Preliminary data suggest that some of these genes may be involved in sex-specific behavioral patterns, although further evidence is still needed. We also began to examine the localization of the ranscripts and translational products in the brain for some of the sexually dimorphic genes.

  • Research Products

    (6 results)

All 2010 2009 Other

All Presentation (5 results) Remarks (1 results)

  • [Presentation] メダカの脳における性差と性分化.2010

    • Author(s)
      大久保範聡
    • Organizer
      日本動物学会第81回大会
    • Place of Presentation
      東京都目黒区,東京大学(招待講演)
    • Year and Date
      2010-09-24
  • [Presentation] Sex difference and its plasticity in the expression of aromatase in the medaka brain.2010

    • Author(s)
      大久保範聡
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      京都府京都市,国立京都国際会館(招待講演)
    • Year and Date
      2010-03-27
  • [Presentation] cyp19a2の発現解析から見えてきたメダカの脳の性分化機構.2009

    • Author(s)
      大久保範聡,長濱嘉孝
    • Organizer
      第34回日本比較内分泌学会大会・日本比較生理生化学会 第32回大会合同大会
    • Place of Presentation
      大阪府大阪市,千里ライフサイエンスセンター(最優秀発表賞受賞)
    • Year and Date
      2009-10-23
  • [Presentation] メダカの脳の性分化と性ステロイド2009

    • Author(s)
      大久保範聡
    • Organizer
      博多シンポジウム「内・外環境と生物応答」
    • Place of Presentation
      福岡県福岡市,九州大学(招待講演)
    • Year and Date
      2009-10-09
  • [Presentation] Medaka : a model for the study of brain sex.2009

    • Author(s)
      大久保範聡
    • Organizer
      The Second International Symposium for Fish Growth and Reproduction
    • Place of Presentation
      香港,香港大学(招待講演)
    • Year and Date
      2009-06-21
  • [Remarks] ホームページ等

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Published: 2012-01-26   Modified: 2016-04-21  

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