Super-resolution Raman and IR hybrid vibrational spectroscopy

2022 Fiscal Year Final Research Report

• Project/Area Number: 21K20503
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Multi-year Fund
• Review Section: 0402:Nano/micro science, applied condensed matter physics, applied physics and engineering, and related fields
• Research Institution: The University of Tokushima
• Principal Investigator: KATO Ryo 徳島大学, ポストLEDフォトニクス研究所, 特任助教 (90910513)
• Project Period (FY): 2021-08-30 – 2023-03-31
• Keywords: ラマン分光 / 赤外分光 / チップ増強分光 / 光熱効果

Outline of Final Research Achievements

Biological functions and phenomenon are triggered by chemical reactions or change of chemical structures of molecules in biological samples. Herein, we developed novel hybrid vibrational spectroscopies combining Raman spectroscopy and IR spectroscopy. We developed novel IR spectroscopic systems, in which IR absorption of molecules were probed by visible light, hence Raman scattering and IR absorption of molecules can be obtained simultaneously. We observed complementary vibrational information of biological tissues using our technique.

Free Research Field

振動分光法

Academic Significance and Societal Importance of the Research Achievements

ライフサイエンス分野では、これまで計測技術と計算科学の発展により、生体試料の基本的な化学構造が解明されてきた。本技術は、生命機能を統合的に理解するための次のステップである「その基本構造がどのように変化して機能を発現させるのか、分子内部の結合状態の相互作用が機能にどう影響するのか」を明らかにする基盤技術として位置づけられる。