2012 Fiscal Year Final Research Report
Strategy for treatment of diseases by cell type specific invasive peptides
| Project/Area Number |
22390038
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General physiology
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| Research Institution | University of the Ryukyus |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Mariko 琉球大学, 大学院・医学研究科, 准教授 (40180400)
SUNAGAWA Masanori 琉球大学, 大学院・医学研究科, 助教 (70325835)
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| Co-Investigator(Renkei-kenkyūsha) |
KONDO Eisaku 愛知県がんセンター研究所, 腫瘍病理部, 部長 (30252951)
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| Project Period (FY) |
2010 – 2012
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| Keywords | ペプチド / 癌 / イメージング / 先進医療 |
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| Research Abstract |
We identify novel cell penetrating peptides (CPPs) that are selectively and efficiently incorporated into human tumor cells according to their lineage. Thus, we established the novel technology that isolation of tumor lineage-homing CPPs from a random peptide library generated by mRNA display method.
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Research Products
(6 results)
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[Journal Article] Tumour lineage-homing cell-penetrating peptides as anticancer molecular delivery systems2012
Author(s)
Kondo E, Saito K, Tashiro Y, Kamide K, Uno S, Furuya T, Mashita M, Nakajima K, Tsumuraya T, Kobayashi N, Nishibori M, Tanimoto M, Matsushita M
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Journal Title
Nature Communications
Volume: 3
Pages: 951
DOI
Peer Reviewed
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