2012 Fiscal Year Final Research Report
Molecular mechanisms underlying development and interaction of progenitor cells essential for cardiac outflow tract morphogenesis
Project/Area Number |
22390211
|
Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Pediatrics
|
Research Institution | Keio University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
UCHIDA Keiko 慶應義塾大学, 医学部, 共同研究員 (50286522)
YAMAGISHI Chihiro 慶應義塾大学, 医学部, 共同研究員 (10296618)
TSUCHIHASHI Takatoshi 慶應義塾大学, 医学部, 共同研究員 (10286528)
KODO Kazuki 慶應義塾大学, 医学部, 助教 (10338105)
MAKINO Shinji 慶應義塾大学, 医学部, 特任准教授 (20306707)
YUASA Shinsuke 慶應義塾大学, 医学部, 講師 (90398628)
|
Project Period (FY) |
2010 – 2012
|
Keywords | 小児循環器学 |
Research Abstract |
Two progenitor cell lineages, the cardiac neural crest cells (cNCCs) and the second heart field (SHF), play key roles in development of the cardiac outflow tract (OFT), and their interaction is essential for establishment of completely separated pulmonary
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Author(s)
Kodo K, Nishizawa T, Furutani M, Arai S, Ishihara K, Oda M, Makino S, FukudaK, Takahashi T, Matsuoka R, Nakanishi T, Yamagishi H.
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Journal Title
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Pages: 1703-1711.
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Author(s)
Maeda J, Yamagishi H, Furutani Y, Kamisago M, Waragai T, Oana S, Kajino H, Matsuura H, Mori K, Matsuoka R, Nakanishi T
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Journal Title
Am J Med Genet A
Volume: 155A(11)
Pages: 2641-2646.
Peer Reviewed
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[Journal Article] Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis2010
Author(s)
Uchida K, Aramaki M, Nakazawa M, Yamagishi C, Makino S, Fukuda K, Nakamura T, Takahashi T, Mikoshiba K, Yamagishi H
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Journal Title
PLoS One
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Pages: e12500
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[Journal Article] Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin2010
Author(s)
Fukushima H, Kosaki K, Sato R, Yagihashi T, Gatayama R, Kodo K, Hayashi T, Nakazawa M, Tsuchihashi T, Maeda J, Kojima Y, Yamagishi H, Takahashi T
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Journal Title
Am J Med Genet A
Volume: 152A
Pages: 1919-1924
Peer Reviewed
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