2012 Fiscal Year Final Research Report
Study on the development and validation of behavioral intervention therapy program for psychiatric symptoms in dementia
| Project/Area Number |
22530750
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Clinical psychology
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| Research Institution | Nagoya City University |
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Principal Investigator |
SATO Junko 名古屋市立大学, 大学院・医学研究科, 研究員 (90566233)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAAKI Shutaro 慶應義塾大学, 医学部, 特任准教授 (80315879)
MIMURA Masaru 慶応義塾大学, 医学部, 教授 (00190728)
TATSUMI Hiroshi 愛知学院大学, 心身科学部, 講師 (70514058)
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| Co-Investigator(Renkei-kenkyūsha) |
FURUKAWA Toshiaki 京都大学, 医学研究科, 教授 (90275123)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 認知症 / 精神症状 / 行動的介入療法 / 焦燥感 |
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| Research Abstract |
Agitated behaviors are frequently observed in patients with dementia and can cause severe distress to caregivers. However, little evidence of the efficacy of nonpharmacological interventions for agitated behaviors exists in patients with dementia. The present pilot study aimed to evaluate the behavioral management technique (BMT) program developed by the Seattle Protocols for patients with agitated behaviors in Japan. Eighteen patients with dementia (Alzheimer’s disease, n = 14; dementia with Lewy bodies, n = 4) participated in an open study testing the effectiveness of the BMT program. The intervention consisted of 20 sessions over the course of three months. The primary outcomes were severity of agitation in dementia as measured using the Agitated Behavior in Dementia scale (ABID) and the Cohen-Mansfield Agitation Inventory (CMAI). The BMT program resulted in significant reductions in the total scores of both the ABID and CMAI. Although both the physically agitated behavior scores and the verbally agitated behavior scores of the ABID improved significantly, the psychosis symptoms did not improve after intervention. The BMT program is likely to be beneficial to caregivers suffering from distress as a result of agitated behaviors. In the future, a well-designed study to develop the BMT program more fully is needed.
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[Journal Article] Reduction in white matter before and after the development of delusions of theft in a patient with Alzheimer Disease .2013
Author(s)
Nakaaki, S., Sato, J., Torii, K., Kawaguchi,T,Kawaguchi,A,,Narumoto. J.,Mimura, M.
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Journal Title
J Neuropsychiatry Clin Neursci
Volume: (in press)
Peer Reviewed
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[Journal Article] Neuroanatomical abnormalities before the onset of different types of delusions in a patient with Alzheimer disease.2013
Author(s)
Nakaaki, S., Sato, J., Torii, K., Kawaguchi,T,Kawaguchi,A,, Narumoto.J.,Mimura,M.
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Journal Title
J Neuropsychiatry Clin Neursci
Volume: (in press)
Peer Reviewed
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[Journal Article] Decreased white matter integrity before the onset of delusions in patients with Alzheimer's disease: diffusion tensor imaging.2013
Author(s)
Nakaaki, S., Sato, J., Torii, K., Oka, M., Miyata, J., Mimura, M.
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Journal Title
Neuropsychiatric Disease and Treatment
Volume: 9
Pages: 25-29
DOI
Peer Reviewed
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[Journal Article] Neuroanatomical abnormalities before onset of delusions in patients with Alzheimer's disease: a voxel-based morphometry study.2013
Author(s)
Nakaaki, S., Sato, J., Torii, K., Oka, M., Miyata, J., Mimura, M.
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Journal Title
Neuropsychiatric Disease and Treatment
Volume: 9
Pages: 1-8
DOI
Peer Reviewed
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[Journal Article] Neuropsychological and functional correlates of clock-drawing test in elderlyinstitutionalized patients with schizophrenia.2012
Author(s)
Okamura, A., Kitabayashi, Y., Kohigashi, M., Shibata, K., Ishida, T., Narumoto, J.,Morioka, C., Kitabayashi, M., Kashima, A., Tani, N., Nakaaki S, Mimura M, Fukui, K.
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Journal Title
Psychogeriatrics
Volume: 12
Pages: 242-7
DOI
Peer Reviewed
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[Presentation] 脳形態と拡散テンソル画像によるアルツハイマー病の精神症状出現予測の検討.2012
Author(s)
仲秋秀太郎,佐藤順子,鳥井勝義,阪野公一,根木 惇,宮 裕昭,成本 迅, 山中克夫,辰巳 寛,宮田 淳,川口毅恒,三村 將
Organizer
第27回日本老年精神医学会
Place of Presentation
大宮ソニックシティ
Year and Date
2012-06-21
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