2012 Fiscal Year Final Research Report
Total synthesis and structure-activity relationship study of citridone A, a new potentiator of antifungal miconazole activity
| Project/Area Number |
22590012
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | 合成化学 / 創薬化学 |
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| Research Abstract |
We have achieved total synthesis of citridone A (1), a new potentiator of antifungal miconazole activity. Extension of this chemistry for the structure-activity relationship study successfully produced new citridone A analogs.
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