2012 Fiscal Year Final Research Report
Biochemical and histological characterization of MAGI-1 inneuronal tissues.
| Project/Area Number |
22590097
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biological pharmacy
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| Research Institution | Institute for Developmental Research, Aichi Human Service Center |
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Principal Investigator |
MORISHITA Rika 愛知県心身障害者コロニー発達障害研究所, 神経制御学部, 研究助手 (30393135)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 脳 / 神経細胞 / アダプター分子 / 神経栄養因子 |
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| Research Abstract |
Using the antibody that selectively recognize MAGI-1, we performed biochemical and histological characterization of MAGI-1 in neuronal tissues. We also found that MAGI-1 interacts with p75 NGF receptor (p75NTR) and She phosphotyrosine binding protein, and regulates the NGF dependent neurite outgrowth of PC12 cells.
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[Journal Article] Localization of multidomain adaptor proteins, pl40Cap and vinexin, in the pancreatic islet of a spontaneous diabetes mellitus model, Otsuka Long-Evans Tokushima Fatty rats.2013
Author(s)
Yamauchi M, Sudo K, Ito H, Iwamoto I, Morishita R, Murai T, Kajita K, Ishizuka T, Nagata K.
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Journal Title
Med Mol Morphol.
Volume: 46
Pages: 41-48
DOI
Peer Reviewed
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[Journal Article] Cell biological characterization of a multidomain adaptor protein, ArgBP2, in epithelial NMuMG cells, and identification of a novel short isoform.2012
Author(s)
Murase K, Ito H, Kanoh H, Sudo K, Iwamoto I, Morishita R, Soubeyran P, Seishima M, Nagata K.
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Journal Title
Med Mol Morphol.
Volume: 45
Pages: 22-28
DOI
Peer Reviewed
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[Presentation] SILl, a causative gene of Marinesco-Sjogren syndrome, plays an essential role in establishing the architecture of the developing cerebral cortex.2012
Author(s)
永田浩一, 稲熊 裕, 西村嘉晃, 伊東秀記, 鈴木基正, 浜田奈々子, 水野 誠, 岩本郁子, 森下理香, 熊谷俊幸
Organizer
米国細胞生物学会
Place of Presentation
モスコーンセンター,サンフランシスコ、米国
Year and Date
2012-12-17
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