2012 Fiscal Year Final Research Report
Study to explore drug seeds for cryptosporidiosis
| Project/Area Number |
22590378
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Parasitology (including Sanitary zoology)
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Research Abstract |
Due to the lack of effective chemotherapy, severe cryptosporidiosis especially seen in immune-compromised host is often fetal. To explore drug seeds for the opportunistic infection, a screening method of the drug effect against Cryptosporidiumparvum in a cell culture model was successfully developed. Using the assessment procedure, anti-cryptosporidal efficacy was confirmed in a part of adenosine analogues, including anti-cancer drugs used in clinical sites.
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