2012 Fiscal Year Final Research Report
The molecular epidemiological study on dioxin exposure and prevalence of hypertrophic cardiomyopathy in Vietnam
Project/Area Number |
22659122
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Single-year Grants |
Research Field |
Hygiene
|
Research Institution | Kanazawa University |
Principal Investigator |
|
Co-Investigator(Renkei-kenkyūsha) |
FUJINO Noboru 金沢大学, 保健学系, 准教授 (40361993)
OKAMOTO Rie 金沢大学, 保健学系, 准教授 (50303285)
|
Project Period (FY) |
2010 – 2012
|
Keywords | 環境保健 / 社会医学 / ダイオキシン類 / 肥大型心筋症 / ベトナム / 分子疫学 |
Research Abstract |
This study is a series of epidemiological studies on dioxin exposure and human health effects in Vietnam. The aim of this study is to make clear the prevalence of hypertrophic cardiomyopathy and examine mutations in its genes. Subjects consists of 500 individual men aged over 40 years old in a herbicide contaminated area and a control area, respectively. The first screening was conducted using electric cardiogram. As results, 7 men were suspected as cardiomegaly. Five men among them were examined using ultrasonic equipment. However, no one was found as hypertrophic cardiomyopathy. It would be suggested that the prevalence of hypertrophic cardiomyopathy is not so frequent
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