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2011 Fiscal Year Final Research Report

Analysis on Inhibitory circuit control of critical period-Comparative study in mice and birds.

Research Project

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Project/Area Number 22700358
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Neuroscience in general
Research Institution沖縄科学技術大学院大学 (2011)
The Institute of Physical and Chemical Research (2010)

Principal Investigator

SUGIYAMA Yoko (YAZAKI Yoko)  沖縄科学技術大学院大学, 臨界期の研究メカニズム研究ユニット, 准教授 (00317512)

Project Period (FY) 2010 – 2011
Keywords行動神経学
Research Abstract

The timing of critical period of ocular dominance plasticity in mice are regulated with cortical inhibitory circuit development. In this study we have tested whether this principle can be applied to the critical period in bird song learning. Early GABA enhancement in the developmental birds brain disrupted later song learning in male zebra finches by closing sensory learning period earlier. Here we suggested conserved critical period mechanism, inhibitory circuit control of critical period.

  • Research Products

    (4 results)

All 2011 2010

All Journal Article (1 results) Presentation (3 results)

  • [Journal Article] 感覚情報をもとに神経回路を形成する時期の決定-臨界期を制御する神経メカニズムの解明2011

    • Author(s)
      杉山陽子(矢崎陽子)、ヘンシュ貴雄
    • Journal Title

      実験医学

      Volume: 29(4) Pages: 533-537

  • [Presentation] Inhibitory circuit control of developmental 'critical period'2011

    • Author(s)
      杉山陽子(矢崎陽子)
    • Organizer
      第82回日本動物学会シンポジウム
    • Place of Presentation
      旭川
    • Year and Date
      20110000
  • [Presentation] GABA enhancement prevents an extended sensory learning period by song isolation in juvenile zebra finch2011

    • Author(s)
      Yoko Yazaki-Sugiyama, Jason Kushner, Neal A Hessler, Takao K Hensch
    • Organizer
      The 41th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      Washington DC USA
    • Year and Date
      20110000
  • [Presentation] Bidirectional plasticity in fast-spiking GABAcircuits by visual experience2010

    • Author(s)
      杉山陽子(矢崎陽子)
    • Organizer
      The Fifth International Neural Microcircuitry Conference
    • Place of Presentation
      Tokyo
    • Year and Date
      20100000

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Published: 2013-07-31  

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