2011 Fiscal Year Final Research Report
Development of Bioluminescent Probe for Real-Time Imaging ofTernary Complex Formation in Living Cells
| Project/Area Number |
22750067
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Analytical chemistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
KANNO Akira 東京大学, 大学院・理学系研究科, 助教 (60466795)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 分析化学 / 生体分子 |
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| Research Abstract |
Various chemical processes and signal transductions are mainly executed by protein-protein interaction. Therefore, it is important to monitor protein-protein interactions in living cells non-invasively. In this study, I developed a bioluminescent probe for highly sensitive real-timesensing of the formation of protein ternary complexes in living mammalian cells.
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