2012 Fiscal Year Final Research Report
Analysis on mechanism that translocates p27Kip1 into nuclei in neuronal progenitor cells in vivo
Project/Area Number |
22791001
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Pediatrics
|
Research Institution | Keio University |
Principal Investigator |
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Project Period (FY) |
2010 – 2012
|
Keywords | 神経発生 / 細胞周期 / プロモータ / 神経幹細胞 / 大脳皮質 |
Research Abstract |
p27Kip1, one of the cell cycle regulatory genes, play a critical role in differentiation of neuronal progenitor cells (NPCs). A purpose of this research was to elucidate the mechanism controlling nuclear accumulation of p27Kip1 proteins. We conducted immu
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