2011 Fiscal Year Final Research Report
VASOHIBIN1 expression and function in the nasal tissue
| Project/Area Number |
22791565
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | VASOHIBIN / 鼻腔 |
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| Research Abstract |
Vasohibin-1 has been reported as a novel functional molecules which negatively regulated angiogenesis. It was suggested by our preliminary experiment that Vasohibin-1 might be involved in the expression of the olfactory receptor, so we verified the expression of Vasohibin-1 in the nasal tissue. Although we confirmed Vasohibin-1 expression in mouse nasal tissue by RT-PCR and immunostaining method, it was not observed on olfactory cells but endothelial cells. The result which supported our hypothesis of the regulation the olfactory receptor by Vasohibin-1 was not obtained.
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