2011 Fiscal Year Final Research Report
Meibomian Gland(MG) and Ocular Surface Alterations in Sod1 knock-out(KO) Mice : A Novel Model for Age Related Dry Eye Disease.
| Project/Area Number |
22791694
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Ophthalmology
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| Research Institution | Keio University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | マイボーム腺 / ドライアイ / 酸化ストレス |
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| Research Abstract |
We investigated the alterations of the MG in the SOD1KO mice. SOD1KO caused inflammation, apoptosis, dry eye and corneal damage. The SOD1-KO mouse appears to be a promising model for the study of age related meibomian gland alterations.
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