2011 Fiscal Year Final Research Report

Ca surface modification gives osteoconductivity to ceramics of high mechanical property

Research Project

Project/Area Number	22791894
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Prosthetic dentistry
Research Institution	Kyushu University
Principal Investigator	TARIQUE A. a. 九州大学, 歯学研究院, 学術研究員 (00568983)
Project Period (FY)	2010 – 2011
Keywords	アルミナ / 表面改質 / 骨伝導性
Research Abstract	We examined whether Ca surface modification ranging from molecular to nano order level gave osteoconductivity to ceramics with high mechanical property. As a result of optimization for treatment condition, it was appeared that much Ca ions could be immobilized onto alumina substrate when hydrothermallytreated at 125℃in the presence of 50 mmol^-1 CaC1^2 solution for 7 days. The treated alumina substrate showed spontaneous apatite deposition in simulated body fluid. Response to rat bone marrow cell was investigated so that the response on the treated alumina substrate was significantly higher than those on nontreated alumina substrate.