2011 Fiscal Year Final Research Report

Evidence construction of a new titanium material concept, and research of the recovery method

Research Project

Project/Area Number	22791908
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Prosthetic dentistry
Research Institution	Kanagawa Dental College
Principal Investigator	HORI Norio 神奈川歯科大学, 歯学部, 非常勤講師 (20386832)
Project Period (FY)	2010 – 2011
Keywords	チタン / 表面特性 / インプラント / 細胞接着能 / タンパク吸着能
Research Abstract	Possible changes in biological potential of titanium(Ti) over time have never been addressed, with a presumption that titanium surfaces are stable in biological property, particularly osseointegration capability. The purpose of this research was to test a hypothesis that protein adsorption capacity and cell attractiveness of Ti, which are critical to the process of osseointegration, changes over time before its use. Degrading trend of protein adsorption capacity and osteoblast attractiveness of Ti surfaces during 4 weeks of storage after processing was remarkable. We postulate that immediate action needs to be taken to explore this phenomenon for possible substantial commercial, scientific and research impacts in the field.