Research and development of a preventive drug for vaccine side effects using nanobubble neomacrolide

2023 Fiscal Year Final Research Report

• Project/Area Number: 22K19614
• Research Category: Grant-in-Aid for Challenging Research (Exploratory)
• Allocation Type: Multi-year Fund
• Review Section: Medium-sized Section 57:Oral science and related fields
• Research Institution: Niigata University
• Principal Investigator: Terao Yutaka 新潟大学, 医歯学系, 教授 (50397717)
• Co-Investigator(Kenkyū-buntansha): 中馬 吉郎 新潟大学, 自然科学系, 研究教授 (40372263) ; 牛田 晃臣 新潟大学, 自然科学系, 准教授 (10582976) ; 土門 久哲 新潟大学, 医歯学系, 准教授 (00594350) ; 前川 知樹 新潟大学, 医歯学系, 研究教授 (50625168)
• Project Period (FY): 2022-06-30 – 2024-03-31
• Keywords: ナノバブル

Outline of Final Research Achievements

We began experiments based on the research plan described in the application document, and announced the interim results at nine conference presentations. Based on the interim results and discussions of these conference presentations, I have written 8 international academic papers in English, which have been accepted and published. In other words, it is possible to objectively demonstrate with numerical values that the presentation of the results planned in the application record has generally been achieved smoothly. In addition to the above, we are promoting outreach activities based on the results obtained, and we have already conducted free on-site classes at public junior high schools. Additionally, as part of our outreach activities, we have been able to conduct social contribution activities, such as receiving interviews from NHK TV and newspapers, based on the commitments made in our application documents.

Free Research Field

細菌学

Academic Significance and Societal Importance of the Research Achievements

インパクトファクターの付された査読付きの国際学術ジャーナル（Microbiology and Immunology, iScience, Microbiology and Immunology, Cytokine, Diagnostics, Microbiology Spectrum, Journal of Biological Chemistry, Microorganisms, PLOS ONE）に投稿し，10編の英語の国際学術論文の全てが受理され，公表されるに至っている．本研究成果は，学術界や社会に新規知見の供与をもたらした．