2013 Fiscal Year Final Research Report
Study on the insect male reproduction molecules mechanism from the viewpoint of the sperm-activating factor.
| Project/Area Number |
23380036
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied entomology
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| Research Institution | Kyoto Institute of Technology |
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Principal Investigator |
NAGAOKA SUMIHARU 京都工芸繊維大学, 工芸科学研究科, 助教 (00303933)
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| Co-Investigator(Kenkyū-buntansha) |
SHIRAI Koji 信州大学, 繊維学部, 准教授 (00293499)
YAMAMOTO Koji 九州大学, 農学研究科, 助教 (00346834)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Keywords | 昆虫 / カイコガ / 生殖 / 精子成熟 / プロテアーゼ / 酵素 / 生理活性 / プロテオーム |
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| Research Abstract |
A serine protease called initiatorin (BmIni) is required for sperm activation in the silkmoth, Bombyx mori. It has been expected that BmIni is responsible for the cleavage of seminal and/or sperm proteins, mainly at Arg-Arg sites, and thus is involved in the sperm activation. However, activation of sperm motility has been little known to other insects. (1) To determine the molecular mechanism of signaling pathways for sperm motility, we examined the evidence that BmIni acts on carboxypeptidase B (BmCPB). (2) We found a crucial role for BmIni-like serine protease activity in initiating conserved signaling pathways for sperm activation in many Lepidoptera, Orthoptera, Hemiptera species.
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