2013 Fiscal Year Final Research Report
Cognitive science on individual difference of impulsive behavior
| Project/Area Number |
23500329
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cognitive science
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| Research Institution | Kyoto University |
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Principal Investigator |
NOMURA Michio 京都大学, 教育学研究科(研究院), 准教授 (60399011)
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| Co-Investigator(Renkei-kenkyūsha) |
NOMURA Yasuyuki 横浜薬科大学, 薬学部, 教授 (00034041)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 衝動性 / 運動反応制御 / セロトニン / 遺伝子 / 個人差 / 前頭前野 |
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| Research Abstract |
Present study focuses on these interrelated areas through the lens of the serotonin transporter (5-HTT), looking specifically at the impulsivity in Japanese people. A large number of behavioral genetics studies have demonstrated that individuals carrying the less efficient S allele of the 5-HTTLPR gene have an increased susceptibility to emotion disorders, whereas this risk is much lower in collectivistic societies. A new hypothesis of gene-environment interaction proposed here addresses this mechanism by showing the following: (1) the behavioral regulation of S allele carriers impulsivity is optimized under aversive conditions, which may help them to adapt to collectivistic cultures; and (2) such self-regulatory responses underlied by the prefrontal cortex are modulated by cultural interdependent self-construal and psychosocial factors, such as general trust, all of which are geared toward modulating fear and social pain, and thus may lower the risk for impulsive behavior.
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[Journal Article] COMT Val 158 Met influences the perception of other's pain2012
Author(s)
Himichi, T., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M
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Journal Title
Psychology Research
Volume: 2
Pages: 185-195
Peer Reviewed
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[Journal Article] The effects of the behavioral inhibition and activation systems on social inclusion and exclusion2011
Author(s)
Yanagisawa, K., Masui, K., Onoda, K., Furutani, K., Nomura, M., Ura, M., Yoshida, H
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Journal Title
Journal of Experimental Social Psychology
Volume: 47
Pages: 502-505
Peer Reviewed
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[Journal Article] Does higher general trust serve as a psychosocial buffer against social pain? : A NIRS study of social exclusion2011
Author(s)
Yanagisawa, K., Masui, K., Furutani, K., Nomura, M., Ura, M., Yoshida, H
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Journal Title
Social Neuroscience
Volume: 6
Pages: 377-387
Peer Reviewed
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[Presentation] Involvement of a polymorphism in the 5-HTT gene in impulsive response style in Japanese population2012
Author(s)
Nomura, M., Kaneko, M., Kusumi, I., Canli, T., Koyama, T., Nomura, Y
Organizer
28th World Congress of Collegium Internationale Neuro-Psychopharmacologium (CINP)
Place of Presentation
Stockholm, Sweden
Year and Date
20120000
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[Presentation] Involvement of the 5-HT2A receptor gene polymorphism in trait anxiety, in activity of VLPFC and in impulsivity : a NIRS study2012
Author(s)
Kajimura, S., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M
Organizer
28th World Congress of Collegium Internationale Neuro-Psychopharmacologium (CINP)
Place of Presentation
Stockholm, Sweden
Year and Date
20120000
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[Presentation] COMT Val158Met gene polymorphism influences the perception of others pain2011
Author(s)
Himichi, T., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M
Organizer
Clinical psychopharmacology and neuroscience, 2011, 9, P137. 2th Asian College of Neuropsychopharmacology
Place of Presentation
Seoul, Korea
Year and Date
20110000
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