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2013 Fiscal Year Final Research Report

Hazard of animal meat containing parasites: analysis of a new parasite-toxic food poisoning

Research Project

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Project/Area Number 23500998
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Eating habits, studies on eating habits
Research InstitutionIwate University (2013)
National Institute of Health Sciences (2011-2012)

Principal Investigator

KAMATA Yoichi  岩手大学, 農学部, 教授 (20152837)

Project Period (FY) 2011 – 2013
Keywords食中毒 / 寄生虫 / 住肉胞子虫 / 毒素 / 馬肉 / シカ肉 / アクチン脱重合因子
Research Abstract

Animal meat is generally served as a cocked and processed food, but some countries including Japan have a food habit to eat raw animal meat. "Basashi" is slices of raw horse meat, like sashimi and has been recognized as one of causes for food poisoning. A parasite, Sarcocystis fayeri, wad found in the horse meat that was eaten by patients. A protein was purified and determined its enterotoxic activity. An internal sequence of amino acid of the toxic protein was determined and toxin gene was cloned by the PCR method using degenerate primers designed from the amino acid sequence. The protein has a homology to an actin depolymerizing factor of Toxoplasma and others. Consumption of raw deer meat containing Sarcocystis parasite also caused food poisoning. Based on these facts, a parasite-toxin food poisoning has been proposed as a new category of foodborne diseases.

  • Research Products

    (8 results)

All 2014 2013 2012

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (2 results)

  • [Journal Article] A toxin isolated from Sarcocystis fayeri in raw horsemeat may be responsible for food poisoning2014

    • Author(s)
      Kamata, Y., Saito, M., Irikura, D., Yahata, Y., Ohnishi, T., Bessho, M., Inui, T., Watanabe M., Sigita-Konishi, Y
    • Journal Title

      J. Food Prot

      Volume: 77 Pages: 814-819

    • Peer Reviewed
  • [Journal Article] 犬を終宿主とするSarcocystis シスト抽出物の腸管毒性2013

    • Author(s)
      斉藤守弘, 新井陽子, 鎌田洋一, 小西良子, 橋本勝弘
    • Journal Title

      日獣会誌

      Volume: 66 Pages: 725-727

    • Peer Reviewed
  • [Journal Article] シカ肉中の Sarcocystis が原因として疑われた有症苦情2013

    • Author(s)
      青木佳代, 石川和彦, 林 賢一, 斉藤守弘, 小西良子, 渡辺麻衣子, 鎌田洋一
    • Journal Title

      日本食品微生物学雑誌

      Volume: 30 Pages: 28-32

    • Peer Reviewed
  • [Journal Article] 馬肉中に含まれる住肉胞子虫の危害性消失条件の検討による生食用馬肉を共通食とする食中毒事例の発生防止対策に関する研究2013

    • Author(s)
      原田誠也, 古川真斗, 徳岡英亮, 松本一俊, 八尋俊輔, 宮坂次郎, 斉藤守弘, 鎌田洋一, 渡辺麻衣子, 入倉大祐, 松本 博, 小西良子
    • Journal Title

      食衛誌

      Volume: 54 Pages: 198-203

    • Peer Reviewed
  • [Journal Article] Sarcocystis fayeri シストの酵素消化抵抗性におよぼす温度処理の効果2012

    • Author(s)
      斉藤守弘, 鎌田洋一, 小西良子
    • Journal Title

      動物の原虫病

      Volume: 27 Pages: 32-34

    • Peer Reviewed
  • [Journal Article] 馬の Sarcocystis fayeri 感染状況2012

    • Author(s)
      斉藤守弘, 鎌田洋一, 小西良子
    • Journal Title

      動物の原虫病

      Volume: 27 Pages: 28-31

    • Peer Reviewed
  • [Presentation] 馬肉食中毒の原因寄生虫であるフェイヤー住肉胞子虫の病原性タンパク質の性状2012

    • Author(s)
      鎌田洋一, 入倉大祐, 斉藤守弘, 大西貴弘, 小西良子
    • Organizer
      第154回日本獣医学会
    • Place of Presentation
      岩手大学, 盛岡市
    • Year and Date
      2012-09-14
  • [Presentation] Sarcocystis fayeri による食中毒・下痢のメカニズムと 15kDa タンパク質との関係2012

    • Author(s)
      斉藤守弘, 鎌田洋一, 小西良子
    • Organizer
      第154回日本獣医学会
    • Place of Presentation
      岩手大学, 盛岡市
    • Year and Date
      2012-09-14

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Published: 2015-07-16  

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