2013 Fiscal Year Final Research Report
Designing fullerene-like peptide structures with switching capability of functions
| Project/Area Number |
23510131
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Kobe University |
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Principal Investigator |
TAMURA ATSUO 神戸大学, 理学(系)研究科(研究院), 准教授 (90273797)
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| Project Period (FY) |
2011 – 2013
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| Keywords | ナノ構造 / ペプチド / ナノチューブ / ナノバイオ |
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| Research Abstract |
Various biomolecules, especially proteins, form nano structures by self-assembly, resulting in unique fuctions in nature. Here we have artificially designed tertiary structures, e.g. the fullerene-like cage, by combining helical units. Then we have succeeded in obtaining novel functions such as enzymatic activity, digenstion of amyloid fibrils, aggregating cells without cytotoxity, and binding to rare metals. These functions are expected to resolve serious issues such as diseases and depletion of natural resources, which address the needs of the modern aging society.
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