2014 Fiscal Year Final Research Report

Monitoring of naturally feed contamination of zearalenone in cattle herds and its preventive measures

Research Project

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Project/Area Number	23580441
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Clinical veterinary science
Research Institution	Kagoshima University
Principal Investigator	TAKAGI Mitsuhiro 鹿児島大学, 獣医学部, 准教授 (40271746)
Co-Investigator(Kenkyū-buntansha)	UNO Seiichi 鹿児島大学, 水産学部, 准教授 (50381140) OTOI Takeshige 山口大学, 共同獣医学部, 教授 (30311814)
Research Collaborator	JOHANNA Fink-Gremmels ユトレヒト大学, 獣医学部, 教授國師恵美子鹿児島大学, 大学院連合農学研究科中村正幸鹿児島大学, 農学部, 准教授宮本明夫帯広畜産大学, 畜産学研究科, 教授出口栄三郎鹿児島大学, 共同獣医学部, 教授川村理香川大学, 農学部, 教授志賀慧鹿児島大学, 農学部獣医学科松本大策 (有)シェパード中央家畜診療所蓮沼浩鹿児島大学, 大学院連合獣医学研究科伏見康生鹿児島大学, 大学院連合獣医学研究科岡本光司鹿児島県曽於農業共済組合家畜診療所渡邊麗 (新屋麗) 鹿児島県曽於農業共済組合家畜診療所
Project Period (FY)	2011-04-28 – 2015-03-31
Keywords	ウシ / ブタ / ゼアラレノン / 尿 / マイコトキシン吸着剤 / 繁殖性
Outline of Final Research Achievements	We investigated effects of a commercially available mycotoxin adsorbent (MA) using Zearalenone (ZEN) contaminated herd as a model herd. The results indicate that MA supplementation has beneficial effects in reducing ZEA absorption from the intestine of cattle, reversing hepatic effects. Additionally, our field trials revealed that 1) natural ZEN contamination resulting in urine levels below the threshold value does not affect embryo production in Japanese Black and Holstein cows undergoing superovulation, and 2) the monthly (seasonally) variation of urinary ZEN concentrations existing under the standard dairy farming condition. Moreover, the effects of in vitro exposure of porcine spermatozoa to ZEN were studied by evaluating several parameters of an in vitro fertilization (IVF) system. Overall, the results indicate that prolonged exposure of boar spermatozoa to ZEN up to 1000 μg/l under reduced metabolic conditions does not affect their in vitro function.
Free Research Field	産業動物獣医学