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2014 Fiscal Year Final Research Report

Relationship between alcoholic liver disorders and sudden death

Research Project

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Project/Area Number 23590850
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Legal medicine
Research InstitutionYamaguchi University

Principal Investigator

FUJIMIYA Tatsuya  山口大学, 医学(系)研究科(研究院), 教授 (50219044)

Co-Investigator(Kenkyū-buntansha) LIU Jinyao  山口大学, 大学院医学系研究科, 講師 (60379956)
HAKUCHO Ayako  山口大学, 大学院医学系研究科, 助教 (90593301)
Project Period (FY) 2011-04-28 – 2015-03-31
Keywordsアルコール / 肝障害 / 脂肪肝 / 突然死 / 大酒家 / 心筋症 / 法医学 / アルコール医学
Outline of Final Research Achievements

We studied the relationship between alcoholic liver disorders and sudden death. Rats and Mouse were treated with Liber diet which includes alcohol or sugar of the same calories for 6 weeks. Then animals were divided to the control group, sustained alcohol treated group and alcohol withdrawal group for 1day to 3 weeks. The liver and heart were pathologically examined. As a result, the sudden death occurred in the alcohol withdrawal group for 1 day. The liver revealed fat deposits and myofibroblast proliferation. The heart revealed slight fibrosis between myocytes.

Free Research Field

法医学

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Published: 2016-06-03  

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