2013 Fiscal Year Final Research Report
Noninvasive evaluation of intracranial vessel wall lesions using high-resolution three-dimensional magnetic resonance vessel wall imaging
| Project/Area Number |
23591789
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Iwate Medical University |
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Principal Investigator |
SASAKI Makoto 岩手医科大学, 医学部, 教授 (80205864)
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| Co-Investigator(Kenkyū-buntansha) |
TERAYAMA Yasuo 岩手医科大学, 医学部, 教授 (70146596)
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| Project Period (FY) |
2011 – 2013
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| Keywords | MRI / 血管壁 / 頭蓋内動脈 / 動脈硬化 / 動脈解離 |
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| Research Abstract |
We attempted to evaluate intracranial arterial wall lesions by using a T1-weighted three-dimensional vessel wall imaging (3D-VWI) technique. In patients with acute non-cardioembolic stroke in middle cerebral artery (MCA) territory, wall thickening of the MCA, which is suggestive of atherosclerotic plaques, was observed in all the patients. In addition, signal intensity of the plaque was significantly increased in the ipsilateral MCA and in the patients with atherothrombolic infarction. In patients with acute vertebrobasilar artery dissection, characteristic findings such as luminal stenosis, aneurysmal dilatation, and intramural hematoma were readily depicted on 3D-VWI when compared with conventional imaging techniques. The 3D-VWI technique can directly visualize intracranial arterial wall lesions in patients with ischemic stroke and dissection, and can be helpful to diagnose these disorders particularly in the acute period.
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[Journal Article] Evaluating middle cerebral artery athero- sclerotic lesions in acute ischemic stroke using magnetic resonance T1-weighted 3-dimensional vessel wall imaging2014
Author(s)
Natori T, Sasaki M, Miyoshi M, Ohba H, Katsura N, Yamaguchi M, Narumi S, Kabasawa H, Kudo K, Ito K, Terayama Y
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Journal Title
J Stroke Cerebrovasc Dis
Volume: 23
Pages: 706-711
Peer Reviewed
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