2013 Fiscal Year Final Research Report
Significance of meso-pancreatoduodenum for en bloc resection of pancreatic head carcinoma
| Project/Area Number |
23592005
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Digestive surgery
|
|---|
| Research Institution | Kanazawa University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
OHTA Tetsuo 金沢大学, 医学系, 教授 (40194170)
GABATA Toshifumi 金沢大学, 医学系, 教授 (00169806)
I Tsutomu 首都大学東京, 人間健康科学研究科, 教授 (70334753)
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Keywords | 膵頭部癌 / Mesopancreatoduodenum / 腎筋膜前葉 / 後方組織への浸潤 / リンパ行性進展 / 直接浸潤 / 上腸間膜動脈神経叢 / 膵頭神経叢 |
|---|
| Research Abstract |
Resection of lymphatic basin and clearance of direct invasion are required for curative resection of pancreatic carcinoma. The anterior renal fascia acts as a barrier against retropancreatic invasion. The principle underlying our surgical strategy for resectable pancreatic head carcinoma is total excision of the lymphatic basin of the pancreatic head, which is termed meso-pancreatoduodenum (meso-pd). Our meso-pd concept refers to the mesentery of the pancreatic head and the duodenum, which is a firm and well-vascularized perineural lymphatic layer located dorsal to the pancreas that reaches behind the mesenteric vessels. The meso-pd is fan-shaped and its trunk is the inferior pancreatoduodenal artery, which is a tributary of the SMA. Therefore, a total meso-pd resection was performed with respect to the PLX surrounding the SMA and including the anterior renal fascia.
|
