2013 Fiscal Year Final Research Report
Animal implant research on small suturing device which eliminates knot tying
| Project/Area Number |
23592029
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | The University of Tokyo |
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Principal Investigator |
ONO Minoru 東京大学, 医学部附属病院, 教授 (40270871)
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| Co-Investigator(Kenkyū-buntansha) |
SAKUMA Ichiro 東京大学, 大学院工学系研究科, 教授 (50178597)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 低侵襲手術 / 冠状動脈バイパス術 / 内視鏡手術 / ロボット手術 |
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| Research Abstract |
We developed a new suturing device which enables to perform coronary artery bypass surgery under endoscopic and/or robotic assistance. First, we confirmed sufficient stretch-resistant forces and acceptable biological safety of this device. Then, we created chronic models of rabbit carotid artery bypass using jugular vein and swine off-pump coronary artery bypass using bilateral internal thoracic arteries, comparing regular suture and this new device. Graft patency and grade of inflammatory cell infiltration were similar between two groups. Thereby, it was shown that this new suturing device is safe and effective. Evaluation of efficacy of this suturing device in endoscopic and/or robotic condition is warranted.
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