2013 Fiscal Year Final Research Report
| Project/Area Number |
23592329
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TAKAYAMA Tatsuya 自治医科大学, 医学部, 准教授 (90324350)
TAKAOKA Naohisa 浜松医科大学, 医学部, 特任研究員 (30467229)
SUGIYAMA Takayuki 浜松医科大学, 医学部, 助教 (70444346)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 腫瘍学 |
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| Research Abstract |
We are searching a marker gene of kidney cancer and we pay attention to brain type fatty acid-binding protein (FABP7) as the candidate and push forward a study. We performed analysis about the influence of long chain unsaturated fatty acid on a kidney cancer thence. High concentration of long chain unsaturated fatty acid tends to suppress cell proliferation of kidney cancer cell strains, and these inhibitions tend to occur at low concentration with the omega-3 fatty acid than the omega-6 fatty acid. In addition, inhibition of cell proliferation with the DHA occurred with low concentration when cells expressed FABP7 gene. It would expect that expression of FABP7 gene would restrain cell proliferation of a kidney cancer at the condition adding the DHA.
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Research Products
(21 results)
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[Journal Article] 腹腔鏡下根治的腎摘除術を施行したpT1N0M0腎癌の長期成績2013
Author(s)
高山達也,甲斐文丈,杉山貴之,永田仁夫,鶴信雄,古瀬洋,伊原博行,栗田豊,麦谷荘一,牛山知己,鈴木和雄,大園誠一郎
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Journal Title
Jpn J Endourol
Volume: 26
Pages: 83-86
DOI
Peer Reviewed
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[Journal Article] Characteristics of aggressive variants in T1a renal cell carcinoma2011
Author(s)
Takayama T, Sugiyama T, Kai F, Suzuki T, Nagata M, Imanishi T, Mizuno T, Sato S, Furuse H, Mugiya S, Ozono S
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Journal Title
J Cancer Res Clin Oncol
Volume: 137
Pages: 9-1653
DOI
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