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2013 Fiscal Year Final Research Report

Detection of carcinoma cells in peripheral circulation by oncolgtic virus therapy

Research Project

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Project/Area Number 23592944
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Surgical dentistry
Research InstitutionShowa University

Principal Investigator

KAMATANI Takaaki  昭和大学, 歯学部, 講師 (00315003)

Co-Investigator(Kenkyū-buntansha) KONDO Seiji  昭和大学, 歯学部, 准教授 (10432634)
MUKUDAI Yoshiki  昭和大学, 歯学部, 助教 (50325099)
KURIHARA Yuuji  昭和大学, 歯学部, 助教 (90514969)
Project Period (FY) 2011 – 2013
Keywords口腔癌
Research Abstract

In this study, we investigated the detection of peripheral circulating tumor cells by an adenovirus included the GFP gene and the hTERT gene infected to oral carcinoma cells in circulating tumor cell model. Although we could confirm fluorescence in oral carcinoma cells, there were no relation between fluorescence and mRNA expression or protein expression. These results indicated that oral carcinoma cells would be circulate in peripheral blood flow in a certain period.

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Published: 2015-07-16  

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