2012 Fiscal Year Final Research Report
Development oftransplanted cell-tracking system usinMgRI
| Project/Area Number |
23659025
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Physical pharmacy
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| Research Institution | Sojo University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HIRAI Toshinori 熊本大学, 大学院・生命科学研究部, 准教授 (40274724)
TERASAWA Hiroaki 熊本大学, 大学院・生命科学研究部, 教授 (10300956)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 非侵襲性イメージング / 細胞移植 / 細胞トラッキング / MRI |
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| Research Abstract |
Stable isotope13C-labeled human glioma cells were prepared by adding essential amino acid 13C-methionine in cell culture media. After subcutaneous transplantation of the cellsin mouse, we use a magnetic resonance imaging at 7T and obtained a chemical sift imaging of the13C-labeled cell cluster1.H/13C-CryoProbe in place of 1tHh/e13C-surface coil enablesus to reduce the scanning time significantly.metThoids may beuseful assaafe celltracking technique in postoperative management of cell transplant therapy.
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Research Products
(6 results)
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[Journal Article] Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneousN-terminus、Acta Crystallogr.2012
Author(s)
Y. Koga, M. Inazato, T. Nakamura, C. Hashikawa, M. Chirifu, A. Michi, T. Yamashita, S. Toma, A. Kuniyasu, S. Ikemizu, Y. Nakabeppu, Y. Yamagata
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Journal Title
Sect F Struct. Biol. Cryst. Commun.
Volume: 69
Pages: 45-48
DOI
Peer Reviewed
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