2011 Fiscal Year Final Research Report
Establishment of detection system of MRD by FACS and analysis of leukemic stem cells in AML
| Project/Area Number |
23659296
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Laboratory medicine
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
IWAMOTO Shoutarou 三重大学, 医学部附属病院, 助教 (20456734)
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| Co-Investigator(Renkei-kenkyūsha) |
ITOU Hiroshi 京都大学, 医学研究科, 助教 (20362387)
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| Project Period (FY) |
2011
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| Keywords | 臨床血液学 / 急性骨髄性白血病 / 微小残存病変 / フローサイトメトリー |
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| Research Abstract |
The aim of this study is to establish new flowcytometric assay to detect minimal residual disease(MRD) of acute myeloid leukemia(AML) cells in children. We established this new assay system for sensitivity one cell in 104 cells by using 16 different antibodies. We started this assay for AML samples in JPLSG clinical trials.
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