2012 Fiscal Year Final Research Report
Analysis of molecular forces for stem/progenitor cell homing in bone regeneration
| Project/Area Number |
23659915
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HIBI Hideharu 名古屋大学, 大学院・医学系研究科, 准教授 (90345885)
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| Project Period (FY) |
2011 – 2012
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| Keywords | SDF-1 / 幹細胞 / 骨延長 |
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| Research Abstract |
In distraction osteogenesis, SDF-1 plays an essential role in the reconstruction of the neovascular network. Blood flow in the distraction gap is reduced by SDF-1 suppression. Then, it was changed to endochondral ossification style from membranous ossification style. On the other hand, experimental results on SDF-1 over-expression experiments, possibilities to promote tissue regeneration by applying the migration cell system, a new medical device provided was suggested.
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Research Products
(8 results)
