2013 Fiscal Year Final Research Report
The molecular epidemiologic analysis of the mechanism of calculus formation: Role of the bacteria exist in saliva
| Project/Area Number |
23659992
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Social dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HANADA Nobuhiro 鶴見大学, 歯学部, 教授 (70180916)
NOMURA Yoshiaki 鶴見大学, 歯学部, 准教授 (90350587)
IMAI Susumu 鶴見大学, 歯学部, 講師 (80072958)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 石灰化 / 口腔細菌 / 歯石 / コリネバクテリウム / グラム陽性桿菌 / 界面活性剤 |
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| Research Abstract |
Corynebacterium matruchotii plays an important role in calcification of the biofilm. However, there are few epidemiological survey and clinical data in the association between C. matruchotii and carculus deposition.Because, a simple immunological detection method of C. matruchotii has not been developed.In this study, we aimed to find a specific antigen of C. matruchotii. The antigen will work for development of an immunological detection method.Twenty types of calcium-binding membrane proteins of C. matruchotii were isolated in this study. Those membrane proteins can be classified into acid proteins.
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