2012 Fiscal Year Final Research Report
Japanese rice wine (Sake)-derived components has anti-inflammatory effect on dextran sulfate sodium (DSS)-induced acute colitis in mice
Project/Area Number |
23700913
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Eating habits, studies on eating habits
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Research Institution | Kyoto Prefectural University |
Principal Investigator |
WADA Sayori 京都府立大学, 大学院・生命環境科学研究科, 講師 (60420709)
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Project Period (FY) |
2011 – 2012
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Keywords | 特殊栄養食品 / 炎症性腸疾患 |
Research Abstract |
The number of Inflammatory bowel disease (IBD) patients is increasing and the change in eating habit is one of the factor of these increasing. It has been reported that several fermented foods have improving effect of IBD. We determined the anti-inflammatory effect of Japanese rice wine-derived peptide on dextran sulfate sodium (DSS)-induced acute colitis in mice. Some peptide derived from Japanese rice wine showed the colitis improving effect at the concentration of few mg/kg/day. This result indicates that Japanese sake-derived components have a potent of therapeutic agent on IBD.
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Research Products
(8 results)
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[Presentation] Absorption of food-derived anti-inflammatory peptide, pGlu-Leu, from gastric intestinal tracts2012
Author(s)
Kiyono T, Bou Y, Fukunaga S, Wada S, Takagi T, Naito Y, Yoshikawa Y, Park E.Y., Nakamura Y, Sato K
Organizer
International Conference on Food Factor
Place of Presentation
Hawaii, USA
Year and Date
2012-12-04
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