2012 Fiscal Year Final Research Report
Development of the Continuous Microflow Reaction and Multi StepProcess
| Project/Area Number |
23750099
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Synthetic chemistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
UENO Masaharu 東京大学, 大学院・理学系研究科, 助教 (80361509)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 合成化学 / 触媒・化学プロセス / マイクロ・ナノデバイス / 連続プロセス |
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| Research Abstract |
We have developed a silver or zinc catalyzed asymmetric allylation reactions, asymmetric Michael reactions of thiols with enones and enantioselective boron conjugate additions in water. These reactions are suitable for continuous microflow reaction. Moreover, we have developed immobilized zinc catalyst for allyration reactions, and an application to flow synthesis. After optimization of flow rates, concentration of solutions, and other conditions, an excellent yield, also with good productivity were obtained.
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Research Products
(18 results)
