2012 Fiscal Year Final Research Report
Development of microsome electrode for efficient drugMetabolism assay
| Project/Area Number |
23790065
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Physical pharmacy
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
MIE Yasuhiro 独立行政法人産業技術総合研究所, 生物プロセス研究部門, 主任研究員 (00415746)
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| Project Period (FY) |
2011 – 2012
|
| Keywords | 電気化学アッセイ / ミクロソームアッセイ |
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| Research Abstract |
Microsome containing human cytochrome P450s (CYPs) play the most crucial role in drug metabolism. Single nucleotide polymorphisms of CYPs are partially responsible for differences in drug effects among individuals. Also, drug metabolism via the microsome
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