2012 Fiscal Year Final Research Report
olecular mechanisms of protein transport through photoreceptor cilia in light/dark adaptation
| Project/Area Number |
23790348
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
General medical chemistry
|
|---|
| Research Institution | Osaka University (2012)
Osaka Bioscience Institute (2011) |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 網膜 / 視細胞 / 繊毛 / IFT / ゼブラフィッシュ |
|---|
| Research Abstract |
We found that diversity of functional relationships between vertebrate ciliary kinesin motors, and our data shows that the repertoire of kinesin motors changes in some cilia during their differentiation. We also identified ectopic accumulation of transducin in the retinal outer nuclear layer of Mak deficient mice, suggesting the possibility that involvement of Mak in the molecular mechanism of transducin transport through cilia between the photoreceptor outer segments and inner segments.
|
Research Products
(13 results)
-
[Journal Article] Presynaptic dystroglycan- pikachurin complex regulates t he proper synaptic connection between retinal photoreceptor and bipolar cells2012
Author(s)
Omori Y, Araki1 F, Chaya T, Kajimura N, Irie S, Terada K, Muranishi Y, Tsujii T, Ueno S, Koyasu T, Tamaki Y, Kondo M, Amano S, Furukawa T
-
Journal Title
J Neurosci
Volume: 32
Pages: 6126-6137
DOI
Peer Reviewed
-
-
[Journal Article] an osteoblast induction factor, plays an essential role for bone formation in association with reduced osteoblastogenesis. Development2012
Author(s)
Mizuhashi K , Kanamoto T, Ito M, Moriishi T, Muranishi Y, Omori Y, Terada K, Tsujii T, Tani A, Komori T, Furukawa T,OBIF
-
Journal Title
Growth and Differentiation
Volume: 54
Pages: 474-480
DOI
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
